There have been no significant changes in the Ebola virus

        Ebola is sweeping West Africa, and researchers fear the virus could become even more difficult to mutate. But a new study shows that, compared to the initial infection and outbreak in March 2014, October to November from Mali (Mali) infected with Ebola virus genome sequence in vivo did not significantly change.
        Clinical trials, diagnosis, antibody therapy, and vaccine development are based on specific sequences of the Ebola genome. If genetic changes are excessive, it will make clinical symptoms more complex (or increase the virus's ability to infect) and lead to the failure of existing therapies and prevention. But the U.S. National Institute of allergy and infectious diseases (National Institute of Allergy and Infectious Diseases) virologist Heinz Feldmann et al we sequenced 4 samples obtained from the recent Ebola Mali, the virus was found almost no variation.
        However, the contrary is that in August last year, a research team of 99 cases of infection in the Sierra Leone Ebola sample sequences and the samples of the virus, a virus is found in the process of interpersonal communication changes appeared in more than 300 genes (Science 29, August 2014, p.989).
        Feldmann et al. (published in Science) (Science) samples of sequenced studies of infection in Mali collected in a number of regions and time periods, thus observing the long-term evolution of ebola. The results confirm most scholars' conjecture that most of the mutations that have been produced will disappear because they are not beneficial mutations.
        The Ebola virus spread from Guinea to Mali two times last year and caused a pandemic. Last October, the two year old girl from her family from Guinea to Calles (in Western Mali) was confirmed infected with the Ebola virus, then died, but did not cause any infection. A few days later, however, a male Ebola virus from Guinea to Mali's capital, Bamako, led to an outbreak that killed at least seven people.
        Feldmann et al. Subsequent to the girls and three infection in second outbreak of Ebola samples was found, and the March 2014 outbreak of the difference between girls only 15 nucleotides between early viral infection. In addition, although there was no evidence of any link between the two outbreaks, the virus that caused the two outbreak in Mali was also very similar.
        University of Calif Santa Cruz (University of California, Santa Cruz) (virology professor had established the Ebola virus genome database) Jim Kent said, the study shows that the Ebola virus is relatively stable, so may develop a vaccine for prevention and control.
        Massachusetts Institute of Baird (Broad Institute in Cambridge Massachusetts Kristian (Andersen) of the Sierra Leone Ebola infection common communication the author of research papers is sequencing) warned that the introduction of experimental therapies and vaccines will choose to add new pressure, therefore continuous monitoring for the evolution of the virus is still very necessary.