Apoptosis "bring disaster to the fish in the moat"

        A team of researchers from three of France's leading bodies found that apoptosis had more influence on the surrounding tissues than previously expected, which could lead to more changes in cell tissue.
        The findings were published online January 22nd in the Journal Nature. The study describes how a fluorescent myosin, which undergoes cell death, changes, and its effects on the environment, as well as folding changes in the epithelium.
        For many years, biologists believe that when cells die (or die), they simply contract, break down, and disappear. Recent studies have found that the process actually has a lot to do, and that the process depends on where it appears in the body.
        Epithelial cells, for example, make up epithelial tissue, the cells that divide the body cavity. The researchers found that the dying cells still maintain the physical connection between the cell and the living cells, and they also pull cells to deform it. But the new study provides further insights reveal this process, researchers through analysis of Drosophila larval stage of leg joint a new point of view, this position is pointed out by previous studies of apoptosis region.
        To better understand the effects of apoptosis on the development of fruit flies, researchers modified fluorescent labels to make them easier to observe. Using this new marker, the researchers found that the protein accumulated into the basal axis of the polarized center of the dying cell. These cells also exert force on the cells around them, increasing levels of myosin in the surrounding cells, causing them to contract and then fold. In addition, the researchers found that in the dying cells, myosin function was suppressed, and myosin changes in the surrounding cells, making cells more likely to be pulled.
        These findings suggest that apoptosis is not just a simple process of cell birth and death, but an important component of fruit maturation in drosophila. The same is true for us, and it is clear that apoptosis is involved in the process of tissue change and plays a major role in the formation of tissues.
        In addition to apoptosis, changes in cell size are also a long existing puzzle in cell biology. Recently, a team of American researchers designed a micro device to isolate and manipulate individual cells that allow them to track the development of hundreds of thousands of bacterial cells. They monitored the growth and division of tens of thousands of Escherichia coli and Bacillus subtilis under strict conditions of stable growth. This experiment has given them thousands of times the sample size of previous studies, and on this basis, they have conducted an unprecedented quantitative study.
By building mathematical models that match experimental data, researchers found that cell growth follows a growth law - exponential growth at constant rates. They were surprised to find that cells are not sensitive to the space or time, they split to follow the "cell size control principles for the quantification of" unique and simple: no matter how the new cell size, each generation will add the same volume to the group, the growth principle of automatic to ensure the stability of different cell distribution the.
        ​The significance of the study will be more than just finding answers to basic scientific questions. Scientists say that understanding the triggers of cell division allows researchers to better understand the process of cancer causing cell division out of control.